This blog is where we share stories, announcements, and insights from around the iGEM community.
All tagged Technology
Due to their inherent safety, simplicity and portability , cell-free systems have become an increasingly important tool in iGEM and synthetic biology more broadly.
Have you ever worked on a laptop computer? (perhaps you are reading this post on a laptop right now?) Have you ever used a cell phone to take a picture? Or get directions using your GPS? Have you ever had your temperature taken in your ear? Or lived in a home with a smoke detector? Or rested your head on a memory foam pillow? If you answered yes to any of these questions, then you are the beneficiary of space innovation!
Software plays a transformative role in driving advances in synthetic biology. From designing biological systems and automating lab equipment, to managing collaborations and analyzing vast amounts of data, software underpins many of the essential tasks in making biology easier to engineer.
While all iGEM teams push the boundaries of synthetic biology, teams who undertake plant projects must overcome a challenge that is particular to plants – namely, that plants take a long time to grow. One reason iGEM teams are successful in pioneering plant synthetic biology is because the teams that have come before have expended effort to get plants to grow within the timeframe of an iGEM Competition season. In honor of the 20th year of iGEM, we thought we’d take a look back on the achievements of some of the teams that have pioneered plant synthetic biology.
Hardware, Software, Wetware – all are encompassed within the Design-Build-Test-Learn cycle of synthetic biology. In honor of 20 years of iGEM, we’d like to feature the Hardware developed by iGEM teams.
Twenty years ago, scientists were using an ad hoc approach to assemble genetic constructs, which required a lot of time and did not always work as anticipated. Tom Knight, an engineer by training, thought that applying standard engineering mechanisms could make the assembly of genetic constructs more reliable. And so, in 2003, Tom proposed an assembly method for standard biological parts, or “BioBricks”.
In 2012, George Church, Yuan Gao, and Sriram Kosuri published their work “Next Generation Digital Information Storage” in the journal Science. Using DNA's four-letter nucleotide code of A, G, T, and C to encode the 0s and 1s of a digitized file, they were the first to demonstrate that DNA could be used as a storage medium. Fast forward to today, and you’ll see numerous developments in reading and writing different forms of data on DNA to make DNA storage more efficient and cost effective.
One of the big challenges facing the field of synthetic biology is the ability to obtain reliable and repeatable measurements in different labs – a key component of all engineering disciplines. Over the past several years, iGEMers have been tackling this challenge through the International InterLaboratory (Interlab) Measurement Studies.
